Publications

List of recent publications


Markofski MM, Dickinson JM, Drummond MJ, Fry CS, Fujita S, Gundermann DM, Glynn EL, Jennings K, Paddon-Jones D, Reidy PT, Sheffield-Moore M, Timmerman KL, Rasmussen, BB, and Volpi E. Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women. Exp Gerontol. 2015 May;65:1-7. PMID: 25735236

Timmerman KL, Amonette WE, Markofski MM, Ansinelli HA, Gleason EA, Rasmussen BB, and Mossberg KA. Impaired IL-6 and IL-10 response to exercise in patients with traumatic brain injury. Eur J Appl Physiol. 2015 Jan;115(1):111-8.

Markofski MM, Flynn MG, Carrillo AE, Armstrong C, Campbell WW, and Sedlock, DA. Exercise training-induced decrease in circulating inflammatory CD14+CD16+ monocyte percentage with and without weight loss in overweight and obese adults. Eur J Appl Physiol. 2014 Aug;114(8):1737-48.

Markofski MM and Braun WA. Possible effects of menstrual cycle on contraction-induced muscle damage. J Strength Cond Res. 2014 Sep;28(9):2649.

Markofski MM, Carrillo AE, Timmerman KL, Jennings K, Coen PM, and Flynn MG. Exercise training modifies ghrelin and adiponectin concentrations and is related to inflammation in older adults. J Gerontol A Biol Sci Med Sci. 2014 Jun;69(6):675-81.

Bigley, A.B. & R.J. Simpson (2015). NK-cells and Exercise: Implications for cancer immunotherapy and survivorship. Discovery Medicine [In Press].

Bigley, A.B., Spielmann, G., Agha, N., & R.J. Simpson (2015). The effects of age and latent cytomegalovirus infection on NK-cell phenotype and exercise responsiveness in man. Oxidative Medicine & Cellular Longevity [In Press].

Simpson, R.J. (2015) Fitness deficits in long-term ALL survivors. Blood, 125, 3366-3368.

LaVoy, E.C., C.M. Bollard, P.J. Hanley, D.P. O’Connor, T.W. Lowder, J.A. Bosch & R.J. Simpson (2015). A single bout of dynamic exercise enhances the generation of monocyte-derived dendritic cells. Cellular Immunology, 295, 52-59.

Bigley, A.B. Rezvani, K., Pistillo, M., Reed, J., Kunz, H., Agha, N., Bollard, C.M. & R.J. Simpson (In Press). Acute exercise preferentially mobilizes NK-cells with a highly-differentiated phenotype and augments cytotoxicity against lymphoma and multiple myeloma target cells. Part II: Impact of latent cytomegalovirus infection and catecholamine sensitivity. Brain, Behavior and Immunity, doi: 10.1016/j.bbi.2014

Ingram, L., R.J. Simpson, E. Malone & G. Florida-James (2015). Sleep disruption and its effect on lymphocyte redeployment following an acute bout of strenuous exercise. Brain, Behavior and Immunity, 47, 100-108.

LaVoy, E.C. C.M. Bollard, P.J. Hanley, J.W. Blaney, D.P. O’Connor J.A. Bosch & R.J. Simpson (2015). A single bout of dynamic exercise enhances the expansion of MAGE-A4 and PRAME-specific cytotoxic T-cells from healthy adults. Exercise Immunology Review, 21, 144-153.

Pollonini, L., Padhye, N., Re, R., Torricelli, A., Simpson, R.J. & C.  Dacso (2015). Pulse transit time measured by photoplethysmography improves the accuracy of heart rate as a surrogate measure of cardiac output, stroke volume and oxygen uptake in response to graded exercise. Physiological Measurements, 36, 911-924

Fiuza-Luces, C., Garatachea, N., Simpson, R.J., Berger, N.A., Ramirez, M. & A. Lucia (2015) Understanding graft-versus-host disease: preliminary findings regarding the effects of exercise in affected patients. Exercise Immunology Review, 21, 80-112.

Kunz, H. Bishop, N.C., Spielmann, G., Pistillo, M., Reed, J., Ograjsek, T., Park, Y., Mehta, S., Pierson, D.L. & R.J. Simpson (2015) Fitness level impacts salivary antimicrobial responses to a single bout of cycling exercise.  European Journal of Applied Physiology, 115, 1015-27

Simpson, R.J. and J.A. Bosch. (2014) Exercise immunology: perspectives on aging, health and extreme human performance. Brain, Behavior and Immunity, 39, 1-7. (editorial accompanying the special issue of the journal).

Spielmann, G. Bollard, C.M., Bigley, A.B., Hanley, P.J., Blaney, J.W., LaVoy, E.C., Pircher, H. & R.J. Simpson. (2014) The effects of age and latent cytomegalovirus infection on the redeployment of CD8+ T cell subsets in response to acute exercise in humans. Brain Behavior and Immunity, 39, 142-151.

Bigley, A.B., Rezvani, K., Chew, C., Sekine, T., Pistillo, M., Crucian, B., Bollard, C.M. and R.J. Simpson. (2014) Acute exercise preferentially mobilizes NK-cells with a highly-differentiated phenotype and augments cytotoxicity against lymphoma and multiple myeloma target cells. Brain, Behavior and Immunity, 39, 160-171.

Spielmann, G. Johnston, C.A., O’Connor, D.P., Foreyt, J.P. and R.J. Simpson. (2014) Excess body mass is associated with T-cell differentiation indicative of immune aging in children. Clinical and Experimental Immunology, 176, 246-254.

Crucian, B., Simpson, R.J., Mehta, S., Stowe, R., Chouker, A., Hwang, S., Actor, J.K., Salam, A.P., Pierson, D. and C. Sams. (2014) Terrestrial stress analogs for spaceflight associated immune system dysregulation. Brain, Behavior and Immunity, 39, 23-32.

Brown F.F., Bigley A.B., Sherry C., Neal C.M., Witard O.C., Simpson R.J. and Galloway S.D. (2014) Training status and sex influence on senescent T-lymphocyte redistribution in response to acute maximal exercise. Brain Behavior and Immunity, 39, 152-159.

LaVoy, E.C., Bigley, A.B., Spielmann, G., Rector, J.L., Morrison, M.R., O’Connor, D.P. and R.J. Simpson. (2014) CMV amplifies T-cell redeployment to acute exercise independently of HSV-1 serostatus. Medicine and Science in Sports and Exercise, 46, 257-267.

LaVoy EC, Bollard CM, Hanley PJ, Blaney JW, O’Connor DP, Bosch JA, Simpson RJ. (2015) A single bout of dynamic exercise enhances the expansion of MAGE-A4 and PRAME-specific cytotoxic T-cells from healthy adults. Exerc Immunol Rev, 21,144-53.

LaVoy EC, Bollard CM, Hanley PJ, O’Connor DP, Lowder TW, Bosch JA, Simpson RJ. (2015) A Single Bout of Dynamic Exercise by Healthy Adults Enhances the Generation of Monocyte-Derived-Dendritic Cells. Cellular Immunology 295, 52-59.

LaVoy, E.C., Bigley, A.B., Spielmann, G., Rector, J.L., Morrison, M.R., O’Connor, D.P. and R.J. Simpson. (2014) CMV amplifies T-cell redeployment to acute exercise independently of HSV-1 serostatus. Medicine and Science in Sports and Exercise, 46, 257-267.

Spielmann, G. Bollard, C.M., Bigley, A.B., Hanley, P.J., Blaney, J.W., LaVoy, E.C., Pircher, H. and R.J. Simpson. (2014) The effects of age and latent cytomegalovirus infection on the redeployment of CD8+ T cell subsets in response to acute exercise in humans. Brain Behavior and Immunity, 39, 142-151.

Drummond MJ, Timmerman KL, Markofski MM, Walker DK, Dickinson JM, Jamaluddin M, Brasier AR, Rasmussen BB, Volpi E. Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults. Am J Physiol Regul Integr Comp Physiol. 2013 Aug 1;305(3):R216-23.

Carrillo AE, Flynn MG, Pinkston C, Markofski MM, Jiang Y, Donkin SS, Teegarden D. Impact of vitamin D supplementation during a resistance training intervention on body composition, muscle function, and glucose tolerance in overweight and obese adults. Clin Nutr. 2013 Jun;32(3):375-81

Drummond MJ, Dickinson JM, Fry CS, Walker DK, Gundermann DM, Reidy PT, Timmerman KL, Markofski MM, Paddon-Jones D, Rasmussen BB, Volpi E. Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults. Am J Physiol Endocrinol Metab. 2012 May 15;302(9):E1113-22.

Carrillo AE, Flynn MG, Pinkston C, Markofski MM, Jiang Y, Donkin SS, Teegarden D. Vitamin D supplementation during exercise training does not alter inflammatory biomarkers in overweight and obese subjects. Eur J Appl Physiol. 2012 Aug;112(8):3045-52

Markofski MM and Volpi E. Protein metabolism in women and men: similarities and disparities. Curr Opin Clin Nutr Metab Care. 2011 Jan;14(1):93-7.

Park Y, Prisby RB, Lesniewski LA, Donato AJ, Delp MD. Effects of aging and exercise training on Angiotensin 11-induced vasoconstrcition of rat skeletal muscle arterioles, J Appl Phsiol., Oct;113(7):1091-100. 2012

Park Y, Booth FW, LeeS, Laye MJ, and Zhang C. Physical Activity Opposes Coronary Vascular Dysfunction Induced during High Fat Feeding in Mice. J Physiol (Lond). Sep; 1 ;590(Pt 17):4255-68. 2012

Lee S, Park Y, Zhang C. Exercise Training Prevents Coronary Endothelial Dysfunction in Type 2 Diabetic Mice. Am. J. Biomed. Sci 3(4): 241-252.2011

Lee S, Park Y, Dellsperger KC, Zhang C. Exercise training improves endothelial function via adiponectin-dependent and independent pathways in type 2 diabetic mice. Am J Physiol Heart Circ Physiol. Aug;301(2):H306-14. 2011

Lee S, Park Y, Zuidema MY, Hannink M, Zhang, C. Effects of interventions on oxidative stress and inflammation of cardiovascular diseases. World Journal of Cardiology (invited review), January 26; 3(1 ): 18-24. 2011

Park Y, Yang J, Zhang H, Chen X and Zhang C. Role of PAR2 in the Regulation of TN F-ainduced Endothelial Dysfunction in Type 2 Diabetic mice. Basic Res Cardiol. Jan;106(1):111-23. 2011

LaVoy, E.C., Nieman, D.C. Henson, D.A., Shanely, R.A., Knab, A.M., Cialdella-Kam, L. & R. J. Simpson. (2013) Latent cytomegalovirus infection does not alter innate immune function in response to a 75-km cycling time trial. European Journal of Applied Physiology, 113, 2629-2635.

Pistillo, M., Bigley, A.B., Spielmann, G., LaVoy, E.C., Morrison, M.R., Rahman, M. & R.J. Simpson. (2013) The effects of age and viral serology on gd T-cell numbers and exercise responsiveness in humans. Cellular Immunology, 284, 91-97.

Bigley, A.B., Spielmann, G., LaVoy, E.C. and R.J. Simpson. (2013) Can exercise-related improvements in immunity influence cancer incidence and prognosis in the elderly? Maturitas, 76, 51-56.

Mehta SK, Crucian BE, Stowe RP, Simpson RJ, Ott CM, Sams CF and Pierson DL. (2013) Reactivation of latent viruses is associated with increased plasma cytokines in astronauts. Cytokine, 61, 205-9.

Lavoy EC, Bosch JA, Lowder TW and Simpson RJ. (2013) Acute aerobic exercise in humans increases cytokine expression in CD27- but not CD27+ CD8+ T-cells. Brain, Behavior and Immunity, 27, 54-62.

Pollonini L, Re R, Simpson RJ, Dacso CC. (2012) Integrated device for the measurement of systemic and local oxygen transport during physical exercise. Engineering in Medical Biology Society, 37, 60-3.

Simpson, R.J., Lowder, T.W., Spielmann, G., Bigley, A.B., LaVoy, E.C. and Kunz, H. (2012) Exercise and the aging immune system. Ageing Research Reviews, 11, 404-420. (Invited Submission).

Bigley, A.B., Lowder, T.W., Spielmann, G., Rector, J. Pircher, H. and Simpson, R.J. (2012) NK-cells have an impaired response to acute exercise and a lower expression of the inhibitory receptors KLRG1 and CD158a in humans with latent cytomegalovirus infection. Brain, Behavior and Immunity, 26: 177-186.

Cosgrove C, Galloway SD, Neal C, Hunter AM, McFarlin BK, Spielmann G, and Simpson RJ. (2011) The impact of 6-month training preparation for an Ironman triathlon on the proportions of naïve, memory and senescent T cells in resting blood. Eur J Appl Physiol, 112, 2989-98.

Spielmann, G., McFarlin, B.K., O’Connor, D.P., Smith, P.J.W., Pircher, H. and Simpson, R.J. (2011) Aerobic fitness is associated with lower proportions of senescent blood T-cells in man. Brain Behav Immun, 25, 1521-9. (This paper was selected for a brief commentary in this issue of the journal).

Lavoy EC, McFarlin BK and Simpson RJ. Immune responses to exercising in a cold environment. (2011) Wilderness Environ Med. 22, 343-51.

Simpson, R. J. (2011) Aging, persistent viral infections and immunosenescence: can exercise “make space”? Exerc Sport Sci Rev, 39, 23-33 (Invited Submission).

Navalta J, McFarlin B, Simpson R, Fedor E, Kell H, Lyons S, Arnett S, Schafer M. (2011) Finger-stick blood sampling methodology for the determination of exercise-induced lymphocyte apoptosis. J Vis Exp. 24. pii: 2595.

LaVoy, E.C., Nieman, D.C., Henson, D.A., Shanely, R.A., Knab, A.M., Cialdella-Kam, L. and R.J. Simpson. (2013) Latent cytomegalovirus infection does not alter innate immune function in response to a 75-km cycling time trial. Eurpoean Journal of Applied Physiology, 113, 2629-2635.

LaVoy, E.C., Bosch, J.A., Lowder, T.W. and R.J. Simpson. (2013) Acute aerobic exercise in humans increases cytokine expression in CD27- but not CD27+ CD8+ T-cells. Brain Behavior and Immunity, 27, 54-62.

LaVoy, E.C., McFarlin, B.K. and R.J. Simpson RJ. (2011) Immune responses to exercising in a cold environment. Wilderness and Environmental Medicine 22, 343-351

Bigley, A.B., Spielmann, G., LaVoy, E.C. and R.J. Simpson. (2013) Can exercise-related improvements in immunity influence cancer incidence and prognosis in the elderly? Maturitas,76, 51-56.

Pistillo, M., Bigley, A.B., Spielmann, G., LaVoy, E.C., Morrison, M.R., Rahman, M. and R.J. Simpson. (2013) The effects of age and viral serology on gd T-cell numbers and exercise responsiveness in humans. Cellular Immunology, 284, 91-97.

Simpson, R.J., Lowder, T.W., Spielmann, G., Bigley, A.B., LaVoy, E.C. and H. Kunz. (2012) Exercise and the aging immune system. Ageing Research Reviews, 11, 404-420.

Coen PM, Flynn MG, Markofski MM, Pence BD, Hannemann RE. Adding exercise to rosuvastatin treatment: influence on C-reactive protein, monocyte toll-like receptor 4 expression, and inflammatory monocyte (CD14+CD16+) population. Metabolism. 210 Dec;59(12):1775-83.

Coen, PM. Flynn, MG, Markofski, MM, Pence, BD, Hannemann, RE. Adding exercise training to rosuvastatin treatment: influence on serum lipids and biomarkers of muscle and liver damage. Metabolism. 2009 Jul; 58(7):1030-8.

Timmerman KL, Flynn MG, Coen PM, Markofski MM, and Pence B. Influence of exercise training on CD14+CD16+ monocytes, toll-like receptor 4, and lipopolysaccharide-stimulated TNFα: production in elderly men and women. J Leukoc Biol. 2008 Nov; 84(5):1271-8.

Flynn MG, McFarlin BK, Markofski MM. The anti-inflammatory influence of exercise training. Am J Lifestyle Med. 2007 May-Jun; 1(3):220-35.

Braun WA, Hawthorne WE, Markofski MM. Acute EPOC response in women to circuit training and treadmill exercise of matched oxygen consumption. Eur J Appl PhysioI. 2005 94(5-6):500-.

von Duvillard SP, Braun WA, Markofski M, Beneke R, Leithauser R. Fluids and hydration in prolonged endurance performance. Nutrition. 2004 Jul-Aug;20(7-8):651-6.

Zhang H, Park Y, Liu Y and Zhang C. Coronary and Aortic Endothelial Function Affected by Feedback between Adiponectin and TNF-a in Type 2 Diabetic Mice. Arterioscler Thromb Vase Bioi. 2010 Nov;30(11):2156-63

Yang J, Park Y, Zhang H, Gao X, Wilson E, Zimmer W, Abbott L and Zhang C. Role of MCP-1 in Tumor Necrosis Factor alpha-induced Endothelial Dysfunction in Type 2 Diabetic Mice. Am J Physiol Heart Circ Physiol. 297(4):H1208-16. 2009

Yang J, Park Y, Zhang H, Xu X, Laine GA, Dellsperger KC and Zhang C (*Co-first authors). Feed-forward Signaling of TNF-a. and NFKB via IKKI3 Pathway Induces Insulin Resistance and Coronary Arteriolar Dysfunction in Type 2 Diabetic Mice. Am J Physiol Heart Circ Physiol. 296(6):H1850-8, 2009

Park Y, Wu J, Zhang H, Wang Y and Zhang C. Vascular dysfunction in type 2 diabetes: emerging targets for therapy. Expert Rev Cardiovasc Ther. Mar;7(3):209-13, 2009

Zhang H, Park Y, Wu J, Chen X, LeeS, Yang J, Dellsperger KC and Zhang C. The Role of TNF-alpha in Vascular Dysfunction. Clin Sci (Lond). 116 (3): 219-230, 2009

Park Y, Capobianco S, Gao X, Falck JR, Dellsperger KC and Zhang C. Role of EDHF in type 2 diabetes-induced endothelial dysfunction. Am J Physiol Heart Circ Physiol. 295(5):H1982-8, 2008

Zhang C, Park Y, Picchi A and Potter BJ. Maturation-induced Endothelial Dysfunction via Vascular Inflammation in Diabetic Mice. Basic Res Cardiol. 103(5):407-16. 2008

Gao X, Park Y, Capobianco S, Yang J, Zhang H, Picchi A and Zhang c.· Role of TNF alpha in Prediabetic Metabolic Syndrome Induced Endothelial Dysfunction. 81 World Congress for MICROCIRCULATION (Ed. Julian H Lombard). MEDIMOND S.r.l., International Proceedings., H815R9145: P179-185. 2007

Saitoh S, Kiyooka T, Rogers PA, Dick GM, Rocic P, Swafford A, Viswanathan C, Park Y, Zhang C, Chilian WM. Redox-Dependent Coronary Metabolic Dilation. Am J Physiol Heart Circ Physiol. 293(6):H3720-5, 2007

Gao X, Xu X, Belmadani S, Park Y, Tang Z, Feldman AM, Chilian WM and Zhang C. TNFalpha Contributes to Endothelial Dysfunction by Up-regulation Arginase in 1/R Injury. Arterioscler Thromb Vase Bioi. 27(6):1269-75, 2007.

Starnes JW, Taylor RP, Park Y. Exercise improves postischemic function in aging hearts. Am J Physiol Heart Circ Physiol. 285(1 ):H347-H351, 2003

Park YJ, Lee HJ, Kim YK, Jin YS. The effects of exercise training on MV02 and QTc interval in obese women. Korean J. of Sports Medicine. 17(1) 188-196, 1999 (In Korean)

Kang HJ, Chung ST, Park YJ, Kim MH, Jin YS. The effect of Physical Exercise on V02 max and Blood Lipid Profile in NIDDM. Korean J. of Sports Medicine. 16(2): 313-319, 1998 (In Korean)

Simpson, R. J., S. M. Graham, G. D. Florida-James, C. Connaboy, R. Clement & A.S. Jackson (2010) Perceived exertion and heart rate models for estimating metabolic workload in elite British soldiers performing a backpack load-carriage task. Appl Phys Nut Metab. 35, 650-656.

Booth, S., G. D. Florida-James, B. K. McFarlin, G. Spielmann, D.P. O’Connor and R. J. Simpson (2010) The impact of acute strenuous exercise on TLR2, TLR4 and HLA.DR expression on human blood monocytes induced by autologous serum. Eur J Appl Physiol. 110, 1259-1268.

Simpson, R. J., C. Cosgrove, M.M. Chee, B. K. McFarlin, D.B. Bartlett, G. Spielmann, D.P. O’Connor, H. Pircher & P.G. Shiels (2010) Senescent phenotypes and telomere lengths of peripheral blood T-cells mobilized by acute exercise in humans. Exerc Immun Rev, 16, 40-55.

Esposito LA, Simpson RJ, Strohacker K, Carpenter KC and McFarlin BK. (2010) Defining a longitudinal survival model to examine forced treadmill running as a countermeasure for diet-induced weight gain. Lab Anim, 44, 305-311.

Strohacker K, Simpson RJ, Carpenter KC, Breslin W, and McFarlin BK. (2010) Longitudinal, diet-induced weight gain is associated with increased blood monocytes and reduced TLR4 expression. Int J Exerc Sci 3(3): 134-142.

Simpson, R. J. & K. Guy (2010) Coupling aging immunity with a sedentary lifestyle: Has the damage already been done? - A mini review. Gerontology, 56, 449-458 (Invited Submission).

Simpson, R. J., B. K. McFarlin, C. McSporran, G. Spielmann, B. o’Hartaigh & K. Guy (2009) Toll-like receptor expression on classic and pro-inflammatory blood monocytes after acute exercise in humans. Brain Behav Immun, 23, 232-9.

Simpson, R. J., C. Cosgrove, L. A. Ingram, G. D. Florida-James, G. P. Whyte, H. Pircher & K. Guy (2008) Senescent T-lymphocytes are mobilised into the peripheral blood compartment in young and older humans after exhaustive exercise. Brain Behav Immun, 22, 544-51.

Campbell, J. P., K. Guy, C. Cosgrove, G. D. Florida-James & R. J. Simpson (2008) Total lymphocyte CD8 expression is not a reliable marker of cytotoxic T-cell populations in human peripheral blood following an acute bout of high-intensity exercise. Brain Behav Immun, 22, 375-80.

Wilson, M. R., L. Foucaud, P. G. Barlow, G. R. Hutchison, J. Sales, R. J. Simpson & V. Stone (2007) Nanoparticle interactions with zinc and iron: implications for toxicology and inflammation. Toxicol Appl Pharmacol, 225, 80-9.

Simpson, R. J., G. D. Florida-James, G. P. Whyte, J. R. Black, J. A. Ross & K. Guy (2007) Apoptosis does not contribute to the blood lymphocytopenia observed after intensive and downhill treadmill running in humans. Res Sports Med, 15, 157-74.

Simpson, R. J., G. D. Florida-James, C. Cosgrove, G. P. Whyte, S. Macrae, H. Pircher & K. Guy (2007) High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects. J Appl Physiol, 103, 396-401. (This paper featured in a highlighted topic of the journal entitled: Exercise and Inflammation).

Simpson, R. J., G. D. Florida-James, G. P. Whyte, N. Middleton, R. Shave, K. George & K. Guy (2007) The effects of marathon running on expression of the complement regulatory proteins CD55 (DAF) and CD59 (MACIF) on red blood cells. Eur J Appl Physiol, 99, 201-4.

Middleton, N., R. Shave, K. George, G. Whyte, R. Simpson, G. Florida-James & D. Gaze (2007) Impact of repeated prolonged exercise bouts on cardiac function and biomarkers. Med Sci Sports Exerc, 39, 83-90.

Simpson, R. J., G. D. Florida-James, G. P. Whyte & K. Guy (2006) The effects of intensive, moderate and downhill treadmill running on human blood lymphocytes expressing the adhesion/activation molecules CD54 (ICAM-1), CD18 (beta2 integrin) and CD53. Eur J Appl Physiol, 97, 109-21.

Simpson, R. J., S. C. Gray & G. D. Florida-James (2006) Physiological variables and performance markers of serving soldiers from two "elite" units of the British Army. J Sports Sci, 24, 597-604.

Simpson, R. J., M. R. Wilson, J. R. Black, J. A. Ross, G. P. Whyte, K. Guy & G. D. Florida-James (2005) Immune alterations, lipid peroxidation, and muscle damage following a hill race. Can J Appl Physiol, 30, 196-211.

Whyte, G., K. George, R. Shave, E. Dawson, C. Stephenson, B. Edwards, D. Gaze, D. Oxborough, J. Forster & R. Simpson (2005) Impact of marathon running on cardiac structure and function in recreational runners. Clin Sci (Lond), 108, 73-80.

Published Book Chapters

Davison, G. & R.J. Simpson (2011). “Immunity”. In: Sport and Exercise Nutrition. (Editor: The Nutrition Society) Blackwell Publishing ltd., Cambridge, UK.

Simpson, R.J. & G. Spielmann (2012). “Exercise and Immunosenescence”. In: Immunosenescence: behavioural and psychosocial determinants. (Editors: Bosch, J.A., Phillips, A.C. and Lord J.M.) Springer, NY, USA.

Simpson, R.J. (2012) “Immunosenescence”. In: Encyclopedia of Exercise Medicine in Health and Disease. (Editor: Mooren, F.C.) Springer, NY, USA.

Simpson, R.J. (2013) “Effects of Exercise on Blood Leukocyte Numbers”. In: Exercise Immunology (Editors: Gleeson, M. Bishop, N.C. and Walsh, N.) Routledge, Oxford, UK.

Spielmann, G., Bigley, A.B., LaVoy, E.C. & R.J. Simpson (2013). “Aging Immunity and the Impact of Physical Exercise”. In: Immunology of Ageing. (Editors: Masoud, A. & Rezaei, N.) Springer, NY, USA.

Simpson, R.J. Kunz, H., Agha, N. & R. Graff (In Press) “Exercise and the regulation of immune function”. In: Progress in Molecular Biology Translational Science (PMBTS): Molecular and Cellular Regulation of Adaptation to Exercise (Editor: Bouchard, C), Elsevier, Oxford, UK.